W. David Lee ... [et. al]. -- The MIT Press, -- c2014. --

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ISBN 0262019779 (hardcover : alk. paper)
ISBN13桁 9780262019774 (hardcover : alk. paper)
テキストの言語 英語                  
分類:NDC10版 492.8
本タイトル From X-rays to DNA :
タイトル関連情報 how engineering drives biology /
著者名 W. David Lee ... [et. al].
出版地・頒布地 Cambridge, Mass. :
出版者・頒布者名 The MIT Press,
出版年・頒布年 c2014.
数量 xii, 233 p. :
他の形態的事項 ill. ;
大きさ 24 cm.
書誌注記 Includes bibliographical references (p. [223]-230) and index.
内容注記 An opportunity for greater discovery -- Concurrent engineering and science -- Engineering and the engineer -- Discovery of chromosomes and the submicrometer microscope -- DNA: gels, paper, and columns -- Structure of DNA and proteins: X-ray diffraction -- Observing DNA and protein in action: radioisotope labels -- Transcription and electron microscopy -- Protein and DNA automated sequencing -- Concurrent versus nonconcurrent engineering -- The engineers and scientists of concurrent engineering -- Institutions and teams for concurrent biology and engineering -- Concurrent engineering in the clinic -- Unmet needs: mapping and understanding cell signaling -- Unmet needs: cancer example -- Summing up.
要約、抄録、注釈等 "Engineering has been an essential collaborator in biological research and breakthroughs in biology are often enabled by technological advances. Decoding the double helix structure of DNA, for example, only became possible after significant advances in such technologies as X-ray diffraction and gel electrophoresis. Diagnosis and treatment of tuberculosis improved as new technologies--including the stethoscope, the microscope, and the X-ray--developed. These engineering breakthroughs take place away from the biology lab, and many years may elapse before the technology becomes available to biologists. In this book, David Lee argues for concurrent engineering--the convergence of engineering and biological research--as a means to accelerate the pace of biological discovery and its application to diagnosis and treatment. He presents extensive case studies and introduces a metric to measure the time between technological development and biological discovery. Investigating a series of major biological discoveries that range from pasteurization to electron microscopy, Lee finds that it took an average of forty years for the necessary technology to become available for laboratory use. Lee calls for new approaches to research and funding to encourage a tighter, more collaborative coupling of engineering and biology. Only then, he argues, will we see the rapid advances in the life sciences that are critically needed for life-saving diagnosis and treatment." -- Publisher's description.
著者標目 Drazen, Jeffrey M., 1946-
Sharp, Phillip A.
Langer, Robert S.
Lee, W. David, 1946-
一般件名 Biomedical engineering.
Medicine -- History.
資料情報1 『From X-rays to DNA : how engineering drives biology /』 W. David Lee ... [et. al]. The MIT Press, c2014. (所蔵館:中央  請求記号:F/492.8/F93/F  資料コード:7105842998)
URL https://catalog.library.metro.tokyo.lg.jp/winj/opac/switch-detail.do?lang=ja&bibid=1352015483