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[ 洋図書 ] Immunity : the evolution of an idea /

Alfred I. Tauber. -- Oxford University Press, -- c2017. --

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ISBN 0190651245 (hardback ; acid-free paper)
ISBN13桁 9780190651244 (hardback ; acid-free paper)
無効なISBN等 9780190651268 (ebook)
テキストの言語 英語                  
分類：NDC10版 491.8
個人著者標目 Tauber, Alfred I.
本タイトル Immunity :
タイトル関連情報 the evolution of an idea /
著者名 Alfred I. Tauber.
出版地・頒布地 New York, NY, United States of America :
出版者・頒布者名 Oxford University Press,
出版年・頒布年 c2017.
数量 xx, 303 pages ;
大きさ 25 cm.
書誌注記 Includes bibliographical references (pages [255]-293) and index.
内容注記 A History of the Immune Self -- Whither Immune Identity? -- Individuality Revised -- Immune Cognition -- Eco-immunology -- A New Biology?
要約、抄録、注釈等 "Senior scholar Alfred Tauber argues in this bold account that common approaches to the study of immunology are inherently flawed in its strict dichotomy of the self and non-self, or external invaders. The relationship between what is self and what is non-self is in reality a complex, dymanic, relational one. Autonomous agents are constantly in the midst of dialectical exchanges in which immunity mediates both noxious and benign encounters. Namely: rather than serving to defend an independent entity, immunity participates in an eco-system. Contemporary transplantation biology and autoimmunity have demonstrated phenomena that upset rigid adherence to the self/non-self dichotomy. Placing tolerant immune mechanisms within a broad ecological context has highlighted the balance of co-operative and competitive relationships in which immunity functions. By understanding immunity this way, as a 'symbiotic turn, ' we come to see that immune reactivity (rejection or tolerance) is a second-order response to the cognitive functions of the immune system. Organisms have a complex capacity to respond to environment, and, through Tauber's insignts, we appreciate them more fully when we grasp the flexibility of the borders of organisms. After first providing an overview of the history of immunology, and explaining why the dominant understanding of it is incomplete and limiting, Tauber argues for this new approach to immunology and explains how it will usher in a new biology in which symbiosis is the rule, not the exception."-- Provided by publisher.,"Immunity mediates both defensive and cooperative relations with the environment. Therefore, the traditional focus on host defense misconstrues the full spectrum of immune activities. An alternate model based on immune balance highlights the information processing of immune perception that precedes discriminatory decisions -- to reject, assimilate, or ignore the identified object"-- Provided by publisher.
一般件名 Immunology -- Philosophy.
Allergy and Immunology.
資料情報1 『Immunity : the evolution of an idea /』　Alfred I. Tauber.　Oxford University Press,　c2017. （所蔵館：中央　 請求記号：F/491.8/T22/I　 資料コード：7110378036）
URL https://catalog.library.metro.tokyo.lg.jp/winj/opac/switch-detail.do?lang=ja&bibid=1352031107

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